Carboxylate Interactions Involved in the Disassembly of Tobacco Mosaic Tobamovirus

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Carboxylate interactions involved in the disassembly of tobacco mosaic tobamovirus.

Structural studies of tobacco mosaic tobamovirus (TMV) have identified two coat protein (CP) intersubunit carboxyl-carboxylate interactions and one CP carboxylate-RNA phosphate interaction whose electrostatic repulsion is believed to drive virion disassembly. In this study, the involvement of each interaction in the disassembly process was examined. Site-directed mutagenesis was used to replace...

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ژورنال

عنوان ژورنال: Virology

سال: 1996

ISSN: 0042-6822

DOI: 10.1006/viro.1996.0570